https://www.sciencedaily.com/releases/2019/07/190718112424.htm
2019-07-18T15:24:24+00:00
New research has shown that estrogen is essential to maintaining muscle stem cell health.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190717132812.htm
2019-07-17T17:28:12+00:00
Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. This protective mechanism can be tricked with drugs. Scientists now describe a new therapeutic approaches that can possibly be derived from these results.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190717105313.htm
2019-07-17T14:53:13+00:00
Scientists found that megakaryocytes act as ‘bouncers’ and thus modulate bone marrow niche properties and cell migration dynamics.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190716095551.htm
2019-07-16T13:55:51+00:00
A new biomedical research study finds a transcription factor called Slug contributes to breast cell fitness by promoting efficient repair of DNA damage. The absence of Slug leads to unresolved DNA damage and accelerated aging of breast cells.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190710132002.htm
2019-07-10T17:20:02+00:00
Researchers have discovered how regenerative capacity of intestinal epithelium declines when we age. Targeting of an enzyme that inhibits stem cell maintaining signaling rejuvenates the regenerative potential of an aged intestine. This finding may open ways to alleviate age-related gastrointestinal problems, reduce side-effects of cancer treatments, and reduce healthcare costs in the ageing society by promoting recovery.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190708172404.htm
2019-07-08T21:24:04+00:00
When doctors remove a tumor surgically or use targeted therapies, the cancer may appear to be gone. However, evidence suggests a tiny subpopulation of adaptable cancer cells can remain and circulate through the body to seed new metastasis in far-off locations. A collaborative research project has identified an entirely new class of molecules that shows promise in rooting out and killing those cancer stem cells.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190703121425.htm
2019-07-03T16:14:25+00:00
In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK (1).
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/07/190701144313.htm
2019-07-01T18:43:13+00:00
Stem cell stimulation shows promise as a potential noninvasive stroke treatment, according to new research. If extended to humans, this technique could greatly improve patients’ quality of life.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190627171549.htm
2019-06-27T21:15:49+00:00
Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190627143047.htm
2019-06-27T18:30:47+00:00
Fleeting differences in gene expression between individuals that occur at different points in time during cell development may have consequences on the ultimate risk for disease in mature tissues and cell types.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190627114000.htm
2019-06-27T15:40:00+00:00
Researchers have developed a method to stimulate human stem cells to organize themselves into ordered layers of different cell types. The method is based on microfluidics and can help better understand how tissues are formed in the embryo, setting the stage for fabricating functional tissues and organs for drug testing and transplantation.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190626160334.htm
2019-06-26T20:03:34+00:00
Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia (BPD), which in the most severe cases can lead to lifelong breathing problems and even death. Scientists studied genetic signatures in donated human neonatal lungs by using single-cell RNA sequencing analysis and mouse models of BPD.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190624173818.htm
2019-06-24T21:38:18+00:00
For the first time, scientists can record cells communicating in real time, opening the floodgates for new developments in cell therapy and other areas within cell biology.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190620121354.htm
2019-06-20T16:13:54+00:00
Researchers found that embryonic stem cells commit to a cell fate far more rapidly than anticipated.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190619174516.htm
2019-06-19T21:45:16+00:00
Cell biologists shed light on the very first step stem cells go through to turn into the specialized cells that make up organs. The findings implicate the ability of proteins to hang around in cells — their stability — as a major factor in controlling a stem cell’s state, and in the decision to remain a stem cell or transform into a specialized cell.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190618095409.htm
2019-06-18T13:54:09+00:00
Researchers have discovered the mechanism behind how neural stem cells in fruit flies are activated to stimulate the generation of new brain cells.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190617164648.htm
2019-06-17T20:46:48+00:00
A research team has developed a process that enables 3D printing of biological tissues without scaffolds using ‘ink’ made up of only stem cells.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190617104128.htm
2019-06-17T14:41:28+00:00
Scientists developed a microrobot that can precisely transplant stem cells in various in vivo and vitro environments. Expects to improve the efficiency of treating degenerative neural disorders such as Alzheimer by accurately and safely delivering to a desired location.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190612141407.htm
2019-06-12T18:14:07+00:00
Researchers have, for the first time, duplicated a patient’s blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190607193705.htm
2019-06-07T23:37:05+00:00
Scientists describe how stem cell therapies could help babies with severe intestinal issues.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190606133837.htm
2019-06-06T17:38:37+00:00
Scientists have recreated a critical brain component, the blood-brain barrier, that functioned as it would in the individual who provided the cells to make it. Their achievement provides a new way to make discoveries about brain disorders and, potentially, predict which drugs will work best for an individual patient.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190606133822.htm
2019-06-06T17:38:22+00:00
Scientists have found that neural stem cells use molecules that form a complex called STRIPAK to ‘wake up’ and produce new neurons (nerve cells) and surrounding glial cells in the brain.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190606133807.htm
2019-06-06T17:38:07+00:00
Researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson’s and other neurodegenerative diseases.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190605171408.htm
2019-06-05T21:14:08+00:00
Researchers have developed a unique technique that uses stem cells and flexible implantable bone-stabilizing plates to help speed the healing of large breaks or defects.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190605133505.htm
2019-06-05T17:35:05+00:00
Research has optimized the process of making human brain ‘organoids’ — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain. Researchers can use this reproducible experimental system to test drugs for neuropsychiatric diseases like autism spectrum disorder and schizophrenia directly in human tissues.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190604131238.htm
2019-06-04T17:12:38+00:00
In a landmark study, scientists discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. They looked at hypercholesterolemia, which is the type of high cholesterol that causes very high levels of LDL — the so-called ‘bad’ cholesterol — to circulate in the blood. They identified a new regulatory mechanism in zebrafish models responsible for this increase.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190604131216.htm
2019-06-04T17:12:16+00:00
We all know someone affected by the battle against cancer. And we know that treatments can be quite efficient at shrinking the tumor but too often, they can’t kill all the cells, and so it may come back. With some aggressive types of cancer, the problem is so great that there is very little that can be done for the patients.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190604084844.htm
2019-06-04T12:48:44+00:00
The ability of a developed cell to transform into another type of cell is exceptionally rare. But UVA researchers have discovered this in zebrafish.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190603124713.htm
2019-06-03T16:47:13+00:00
Researchers advancing gene-editing techniques to help patients with sickle cell disease discover an unexpected boost in fetal hemoglobin production, which mutes the effect of the disease.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190603124610.htm
2019-06-03T16:46:10+00:00
A new approach has enabled researchers to create Expanded Potential Stem Cells (EPSCs) of both pig and human cells. The research has incredible potential for studying human development and regenerative medicine. This is the first time scientists have been able to derive stem cells from early pig embryos and will also be beneficial for animal health and food production.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/06/190603124528.htm
2019-06-03T16:45:28+00:00
A study of influenza virus transmission in Nicaraguan households reveals new insights into the type of immune responses that may be protective against influenza virus infection, report investigators. The findings could help scientists design more effective influenza vaccines and lead to the development of novel universal influenza vaccines.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190531085406.htm
2019-05-31T12:54:06+00:00
In ongoing research to find a treatment for acute kidney injury, scientists have further advanced a promising approach using therapeutic factors produced by stem cells by creating a more efficient delivery method that would improve tissue regeneration.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190530122016.htm
2019-05-30T16:20:16+00:00
A stem cell therapy delivered into the nose can restore the sense of smell in a mouse model of olfactory loss. The findings provide proof of principle for an approach that has the potential to be of broad utility for a range of clinical conditions causing loss of olfaction.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190528120542.htm
2019-05-28T16:05:42+00:00
Scientists have revealed the difference between a stem cell and other blood vessel cells using gene-sequencing technology.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190528095255.htm
2019-05-28T13:52:55+00:00
A novel approach reveals vaping’s effect on endothelial cells and the most harmful flavors.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190524113534.htm
2019-05-24T15:35:34+00:00
New research shows that cancer cells of glioblastomas — conspicuously aggressive solid brain tumors — manifest developmental plasticity and their phenotypic characteristics are less constrained than believed.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190523142958.htm
2019-05-23T18:29:58+00:00
Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a new study.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190523104920.htm
2019-05-23T14:49:20+00:00
Meaningful studies are lacking for certain patient groups. Disease-specific registries could help close the data gap.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190522141221.htm
2019-05-22T18:12:21+00:00
Other than clinical observations, the stem cell field lacks a repeatable, time-sensitive, noninvasive tool to assess the effectiveness of transplanted cells in the targeted organ. Researchers analyzed biomarkers secreted from transplanted human stem cells in the recipient blood of a rodent model of heart attack. Analysis of the blood test showed responding cells had changed their gene expression, behavior and secretions, suggesting this liquid biopsy could provide a window into stem cell activity and effectiveness.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190520171622.htm
2019-05-20T21:16:22+00:00
Researchers have identified a new stem cell type that can significantly improve cardiac function.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190516101445.htm
2019-05-16T14:14:45+00:00
A new study challenges traditional knowledge of stem cell development. The study reveals that the destiny of intestinal cells is not predetermined, but instead determined by the cells’ surroundings. The findings may make it easier to manipulate stem cells for stem cell therapy.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190516082354.htm
2019-05-16T12:23:54+00:00
Scientists have now discovered that a certain group of cancer drugs (MEK Inhibitors) activates the cancer-promoting Wnt signalling pathway in colorectal cancer cells. This can lead to the accumulation of tumor cells with stem cell characteristics that are resistant to many therapies and can lead to relapses. The researchers thus provide a possible explanation for why these drugs are not effective in colorectal cancer.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190515131736.htm
2019-05-15T17:17:36+00:00
A study published in the journal Stem Cells describes a new and unexpected way to accelerate the maturation of induced pluripotent stem cells into cardiac muscle cells.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190514143234.htm
2019-05-14T18:32:34+00:00
Scientists have discovered how stem cells can develop resistance against viruses, a finding that could aid the development of stem cell therapies.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190514115823.htm
2019-05-14T15:58:23+00:00
Nerve cells derived from human stem cells often serve as the basis for research into brain diseases. However, these cells differ considerably in their quality and produce varying results. Scientists are therefore looking for simple cell models that lead to consistent results. Researchers describe a new model that consists of only one human nerve cell.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190514104106.htm
2019-05-14T14:41:06+00:00
Researchers have combined embryonic cells and liver cells in a new cell culture test. This combination lets them detect adverse effects that new medications may have on embryos early on in the drug development process.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190510094811.htm
2019-05-10T13:48:11+00:00
Researchers find that ‘waves’ of Hes1 and Ascl1 gene expression control the quiescent and active state of adult neural stem cells. Hes1 expression promotes quiescence and suppresses Ascl1, and knocking out Hes1 increases Ascl1 expression and subsequent adult neural stem cell activation.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190509173337.htm
2019-05-09T21:33:37+00:00
Recent work highlights a better way to grow smooth muscle cells, one of the two cellular building blocks of arteries, from pluripotent stem cells. This research is part of an effort to create artery banks — similar to blood banks common today — with readily-available material to replace diseased arteries during surgery.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190509112251.htm
2019-05-09T15:22:51+00:00
Researchers have developed a stem cell based model in order to study the resilience and vulnerability of neurons in the neurodegenerative disease ALS. The results can aid in the identification of new genetic targets for treatments protecting sensitive neurons.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190509092720.htm
2019-05-09T13:27:20+00:00
Our hair, skin and eyes are colored by a pigment called melanin, which is produced by pigment cells called melanocytes. Scientists have used stem cell technology to successfully create melanocyte precursor cells. These cells can be used in research on melanoma and other pigment cell-related illnesses.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190508134506.htm
2019-05-08T17:45:06+00:00
Researchers used single-cell sequencing to identify a protein expressed uniquely by insulin-producing beta cells created from stem cells in the laboratory. By targeting the protein and adding a physical enrichment method, the purity of beta cells improved from 30 to 80%. Improved control over the beta cell production process will allow researchers to refine cell therapy for patients with type 1 diabetes.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190507110414.htm
2019-05-07T15:04:14+00:00
Scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells (iPSCs), make tiny ‘cargo packets’ able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells. They say the human iPSCs they studied produced much more of the packets, formally known as extracellular vesicles, than other kinds of adult stem cells commonly used for this purpose in research.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190506132924.htm
2019-05-06T17:29:24+00:00
Neurodegenerative diseases like multiple sclerosis (MS) affect millions of people worldwide and occur when parts of the nervous system lose function over time. Researchers have discovered that a type of skin-related stem cell could be used to help regenerate myelin sheaths, a vital part of the nervous system linked to neurodegenerative disorders.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190506093633.htm
2019-05-06T13:36:33+00:00
How do bones heal, and how could they heal better? The answer to these questions may lie in a newly discovered population of ‘messenger’ cells, according to a recent study.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190502143437.htm
2019-05-02T18:34:37+00:00
Researchers have found a way to transform skin cells into the three major stem cell types that comprise early-stage embryos. The work (in mouse cells) has significant implications for modeling embryonic disease and placental dysfunctions, as well as paving the way to create whole embryos from skin cells.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/05/190502143412.htm
2019-05-02T18:34:12+00:00
Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In a new study, scientists describe how cells ‘decide’ which of these two directions to take.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/04/190425143741.htm
2019-04-25T18:37:41+00:00
New findings about an aggressive form of leukemia could aid the development of novel drugs to treat the condition.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/04/190425104312.htm
2019-04-25T14:43:12+00:00
A simple injection that can help regrow damaged tissue has long been the dream of physicians and patients alike. A new study moves that dream closer to reality with a device that makes encapsulating cells much faster, cheaper and more effective.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/04/190424153621.htm
2019-04-24T19:36:21+00:00
A subset of the stem cells in hair follicles have the potential to regenerate the coating that insulates neurons in mice, report scientists.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
https://www.sciencedaily.com/releases/2019/04/190424153527.htm
2019-04-24T19:35:27+00:00
Researchers in Japan have demonstrated preserving frozen animal cells without a cryoprotectant agent, relying instead on ultrarapid cooling.
https://www.sciencedaily.com/news/health_medicine/stem_cells/
